When are Testosterone Therapy Results Seen?

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When are Testosterone Therapy Results Seen?
When are Testosterone Therapy Results Seen?

While psychological effects and increased libido may occur within weeks, effects like changes in body composition like fat loss and muscle mass may require longer time-frames.

Effects on Muscle Mass/ Strength

Studies have shown that testosterone therapy is capable of increasing muscle mass within a few weeks of administration. The degree of effect that this kind of therapy has on muscle mass and strength is hugely dependent on the dosage and frequency that the therapy is conducted with. If the dosage of testosterone is very low, there may be no noticeable effects to muscle mass at all. Research indicates that some muscles are more responsive to testosterone therapy than others.

Lower body muscles like thigh muscles and quadriceps show increases within 12 – 16 weeks depending on the dosage. Skeletal mass and general power has seen to increase over a 180 day span. Lean body mass shows significant positive change within 6 months. Therefore, it can be said that the therapy’s effects include noticeable changes within the first 20 weeks, showing maximum effect between the 6th and the 12th month.

Effects on body composition

Testosterone therapy has also been shown to reduce obesity and weight-gain by increasing lipid metabolism. While body weight, sometimes, may remain unchanged due to an increase in muscle mass, increased levels of testosterone lead to a decrease in fat stored.

Typically, a decrease in total body fat content is registered after 3 months of going through testosterone therapy. This may differ from patient to patient but it is generally assumed that noticeable decrease in fat occurs between 3 and 12 months. This is likely to continue at a slowing rate over the course of 2 years, assuming that the therapy is continued.

Effects on blood pressure

Testosterone therapy has been shown to cause cardiovascular effects and decreased blood pressure between 3 and 9 months. A reduction in arterial stiffness is noticed within just 48 hours and it improves over the course of 3 months. Exercise capabilities of patients with heart conditions improve significantly after approximately 12 weeks. However, it must be noted that when a testosterone dose I too high blood pressure can increase.

Effects of libido

Testosterone is hugely connected with a patient’s libido, sexual desires, and sexual capability. Testosterone therapy is said to cause increased sexual desires, stimulating a patient’s libido within just three to four weeks. This increase grows at a declining rate for about three months.

With regard to erectile functioning, effects have been seen to manifest themselves within 3 weeks to 3 months. Maximum effects are seen after a period of 3 – 6 months of testosterone therapy. In some cases, these effects may be observed close to a year.

Effects on quality of life

A patient’s quality of life is generally measured by conducting surveys and using questionnaires, where patients answer questions regarding their present states of mind. It is also hugely connected with one’s libido and sexual desires. Surveys show that patients show noticeable changes in their dispositions from one month onward and this could continue over a period of 9 -18 months.

Effects on psychology

A patient’s psychology is determined by their predominant moods and their motivation levels, among other factors. Studies have shown that testosterone therapy and increased testosterone levels caused an improvement in patient’s moods over a 3 – 4 week span. Patients noted that they felt the therapy combating depression after around 3 – 6 weeks. This translates into increased sociability, reduced anxiety, increased attention spans, and increased confidence. Fatigue levels also show improvement after a month.

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  1. Ned Albright
    Posted March 28, 2013 at 2:24 pm | Permalink

    I am 74 years old and have had blood tests {2}done for my testosterone level. The results have been that it is “normal for my age”. I am not happy with my libido and want it improved. My urologist and GP say that the “long term effects” of testosterone supplements is “not known”; with no further comments, not even any negative comments.
    Are you aware of any negative effects or suspicions of negative effects of a supplement? Are strength and dosage of supplements determined by present testosterone levels? Please advise and/or direct me to additional information.

    • Dr. Welch
      Posted April 1, 2013 at 3:12 pm | Permalink

      You are correct that your testosterone may be “normal” for your age, but that in fact does not mean it’s “optimal”. We do keep our patients under strict monitoring to make sure that the testosterone levels are not too high. The strength and dosage is tailored to meet each patient’s need based on their current testosterone levels.

      1. What risk are associated with Testosterone Replacement Therapy?
      Although rare, there are some risks with low testosterone therapy. Some patients could experience the following side effects:
      Increase in red blood cells
      ◦This can be beneficial if you have anemia (low blood counts). However, it can be potentially dangerous since too much blood can block your blood vessels and lead to a heart attack or stroke.
      Prostate effects
      ◦Testosterone therapy increases the volume of your prostate gland. To date, there have not been any studies showing that testosterone therapy increases the risk of prostate cancer.
      Skin reactions
      ◦These are most common with use of a patch; however, they lower with the use of a gel and are rare with injections.
      ◦This is common particularly in young men, but usually reversible after stopping testosterone therapy.
      Sleep apnea ◦This is a condition that disrupts breathing during sleep. Although uncommon, it is a reported side effect.
      Fluid retention
      ◦Although uncommon, you must use caution if you have a history of heart failure or kidney disease.
      ◦Acne, oily skin, increased body hair and flushing have also been reported.

  2. Doug
    Posted March 28, 2013 at 4:05 pm | Permalink

    I began HRT a little more then 4 years ago. I have tried gels, implants, and weekly shots. The weekly shots are by far more effective in providing a consistent and predictable level of Testosterone and I currently maintain a regimen of 1ML per week. Since my measurable T level was less the <100 when first tested 4+ years ago we knew cycling wasn't necessary. I am now averaging about a 700 T Level. All the above benefits have been experienced by me and I have seen no negative side effects to date.

    • Dr. Welch
      Posted April 5, 2013 at 1:43 pm | Permalink

      Thanks for your comments. We constantly hear from men who say that injectable testosterone is far more effective than any other form of administration. Sounds like you have found your “sweet spot” at 700! Make sure you get regular blood tests to monitor your PSA, CBC, CMP, E2, Lipids etc etc .

  3. Charles Moore
    Posted March 29, 2013 at 12:27 pm | Permalink

    Can I get these injuctions in Montrose Colorado? from who? Should I get a blood test to see if my T. level is too low prior to injections

    • Dr. Welch
      Posted April 5, 2013 at 1:43 pm | Permalink

      Please let AAG Health know that you want testosterone injections. They have a doctor in Colorado you can go see after a blood test has been performed. AAG Health can also arrange the blood test too!

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