Geref, also known as Sermorelin, is what is known as a growth-hormone releasing analogue. It is used to diagnose and treat disorders in children. Geref by Serono is a discontinued product but pharmacy compounded Sermorelin Acetate is available for prescription in the USA.

As opposed to other growth hormones, Geref stimulates the pituitary gland to secrete growth hormones endogenously. Geref functions on the idea that even children with idiopathic growth disorders may have a functional pituitary gland.

What Geref does

Like many other growth hormones, Geref is used primarily to treat children’s growth disorders. However, it has also been used to treat conditions of dwarfism in adults. Geref, is unlike other growth hormones because it stimulates the pituitary gland itself to produce and secrete the hormones required to combat various conditions. Children who suffer from such disorders, essentially, lack the presence and interaction of various growth hormones and therefore develop many unusual symptoms. Some of these conditions are treatable with the use of Geref.

When there is a growth hormone deficiency in a child, it causes several complications with regard to physiology as well as psychology. Often children with growth disorders may experience stunted growth, a propensity to gain weight, the development of strange physical features like puffy feet, hands, etc., among several other symptoms. Furthermore, these deficiencies may contribute adversely to the mental well-being of the child as well. For example in the case of a child suffering from Prader-Willi syndrome, the patient may experience an unquenchable hunger, thus increasing the risk of obesity greatly.

Geref, as a diagnostic medicine, as well as a treatment, will allow doctors to gauge whether the pituitary gland is functional and also what hormones it is able to produce and secrete. Accordingly, doctors can supplement Geref with other hormones missing from the patient’s physiological profile.

What are its side effects?

Geref, like most other growth hormones, has been known to produce several side-effects. These may include a swelling and pain around the site of the injection. Furthermore, some patients may develop allergies as a result of administration of this drug. Hyperactivity and headaches are also associated with the use of Geref. Other side-effects experienced may include tightness in the chest region, vomiting, development of rashes, dizziness, discomfort in swallowing and breathing, etc. It is also not advisable to use this drug if the patient has a history of cancer.

Where is Geref manufactured?

Geref was first introduced into the market in 1998 by Serono Laboratories in the U.S.A.
It was one of the first growth hormone treatments available. Geref is priced differently across different online medical vendors and clinics but it generally ranges from $300 to $500 for 9 mg.