No Link Between Testosterone Optimization and Blood Clots

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A new study released by The University of Texas shattered the previously held belief about how testosterone optimization, or testosterone replacement therapy, could increase the risk of certain types of blood clots.

Previous observations implied that testosterone optimization led to an increased risk of “deep vein thrombosis” in the legs. The more technical term for this is venous thromboembolism or (VTE). It was also implied that pulmonary embolism or blood clots in the lungs could also be result of testosterone replacement.

In 2014, the FDA insisted that prescription testosterone products carry the following warning label: “could cause an increased risk of VTE.” However, the panel that ordered the labeling did so based on anecdotal accounts of post-market use of the products.

There was no kind of long-term, comprehensive trial created to specifically test the accuracy of the claim.

The Study of Testosterone and Blood Clots

Testosterone Replacement (aka testosterone optimization) May HelpThe recent study done by The University of Texas looked at over 30,000 men who had been diagnosed with and treated for blood clots.

The findings of the study were detailed in the well-respected Mayo Clinic Proceedings. They found that “middle-aged and older men who receive testosterone replacement are not at increased risk” of either VTE or pulmonary emboli.

The researchers tracked and cross-referenced over 30,000 cases of men with blood clot issues  who also enrolled in a particular insurance plan from 2007 to 2012.

They found that testosterone optimization was in no way “associated with an increased risk of VTE.”

In addition, they found a lack of a connection between increased risk and testosterone replacement. None of the typical administration methods of delivering testosterone (i.e. transdermal patches, creams, or intramuscular injections) were associated with any level of increased risk of blood clots.

The research was conducted by The University of Texas Medical Branch at Galveston, and supported by the National Institutes of Health.

Benefits of Testosterone Optimization

In recent years such alleged links between testosterone optimization and increased risk of heart attack, stroke, and prostate cancer have all been proven false.

In fact, testosterone replacement, when properly prescribed and monitored by a qualified physician, is a very safe and effective way to help you to age optimally. Additionally, it is one of the best ways to help you maintain peak performance at any age.

cenegenics cost for testosterone replacement therapy (aka testosterone optimization)Testosterone optimization can help you:

  • Feel younger and stronger
  • Improve cognition
  • Improve sexual performance
  • Strengthen bones and increase muscle mass
  • Reduce depression and anxiety
  • Improve sleep
  • Combat fatigue


But, the only way to know if you can benefit from testosterone optimization is to have your levels checked. Contact our office today for a free consultation, you may even qualify for your first month’s supply of testosterone absolutely FREE!


You can find out a lot more about testosterone optimization and other ways to age optimally in Dr. Gaines’ new full length book, Great Gains For Life.



Have you or anyone you know ever tried a hormone optimization treatment, what were the results?

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  1. Jared
    Posted August 5, 2015 at 10:44 am | Permalink

    This is great news, I have avoided testosterone, even though at 56, I feel like I need it, but I hear so much about dangerous side effects, thank you Dr. Gaines for setting the record straight…

  2. Bill Lander
    Posted August 14, 2015 at 7:26 pm | Permalink

    I’have been on T replacement for two years as a result of the amount of heart related medication stripping T from my body. It’s still goes out nearly as fast as it can be replaced but it certainly makes me feel, and enjoy my life better. a heart attack and the resulting treatment is no excuse not to live your life fully. T replacement let me get back into the swing of life.

    • Dr. Richard Gaines
      Posted August 21, 2015 at 2:05 pm | Permalink

      Hi Bill, I’m so glad to hear this news! I’m also pleased when I hear stories of how hormone therapy has helped people. Thanks for sharing!

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