Proposed Drug for Low Growth Hormone Fails

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growth hormone drug trials

Clinical trials of a proposed drug for low growth hormone have failed to produce adequate results to move forward. Which means that HGH therapy is still the best treatment for low growth hormone.

The trial, which was said to be in the “late stages”, was for a drug being developed by Pfizer in conjunction with OPKO Health, a pharmaceutical company based in Miami. The experimental drug was designed to help fight growth hormone deficiency in adults. According to OPKO, it has “failed to produce statistically significant benefits versus a placebo” in a phase 3 clinical trial.

The trial will continue to see if the drug has positive results for pre-pubescent children suffering from growth hormone deficiency. However, for adults suffering from low HGH, the best treatment remains growth hormone replacement therapy.

What is Growth Hormone?

growth hormone factsHGH stimulates growth in children and teens, and helps to maintain muscle mass and bone strength throughout life. In this way, it really should be described as “Human Repair Hormone.” True, it is fundamental for “growth” in children and teens, but after that, it is still regularly produced by your body, and is essential to the way your body heals and repairs itself.

It is normal for HGH production to decrease over time, and levels to drop significantly in middle age and beyond. This prompted researchers to speculate that low HGH levels could be responsible for some of the weakness, fatigue, and lack of vitality that we experience as we age.

Growth Hormone Therapy and Age Management

Growth hormone FactsWith the successful use of HGH injections in those suffering clinical HGH deficiency, those of us in the field of age-management felt it stood to reason, that Growth Hormone replacement therapy could also be helpful in replenishing what age takes away.

Your body produces less and less human growth hormone as you age. It declines at a rate of about 2%-4% a year. A 20-year-old man makes about 800 micrograms of HGH every day, while an 80-year-old man produces about 60 micrograms each day. That is a significant drop which can contribute to fatigue, weight gain, loss of muscle mass and bone density, poor sleep, and sexual issues.

In 1991, the New England Journal of Medicine published one of the first studies to test the effects of HGH injections on aging. The study was conducted using elderly men.

Lead researcher on the study, Dr. Daniel Rudman, concluded, “We reversed 10 to 20 years of the aging process. We saw fat diminished, muscle tissue increased, and better bone density.”

Patients in this and later studies, also reported a “general feeling of better health,” as evidenced by quality of life scores.

Who Should Consider HGH Replacement Therapy?

 

Growth Hormone Therapy and Age ManagementLike any hormone replacement therapy, HGH replacement therapy is not without its risks and controversies. However, such side-effects usually occurred with people who were abusing HGH, and/or having it administered by unqualified professionals, or having obtained it from disreputable sources.

Which is all the more reason why anyone over 40 who is experiencing symptoms that may be related to adult growth hormone deficiency– fatigue, weight gain, sleep disruption – seek the advice of qualified medical professionals who are experienced with the symptoms of low HGH, and the proper administration of growth hormone therapy.

Only through proper analysis and diagnostics, can doctors get at the root of your aging issues, and then prescribe the most effective treatments for your individual needs and lifestyle, such as hormone replacement therapy.

Human Growth Hormone is just one way that age-management professionals have to give you back what age takes away.

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